Cutaneous Curvularia infection


Moody MN, Tschen J, Mesko M. have published a paper on Cutaneous Curvularia infection of the forearm in Cutis. 2012 Feb;89(2):65-8.

Phaeohyphomycosis is a broad clinicopathologic designation that refers to chronic cutaneous, subcutaneous, or mucosal infection caused by one of several genera and species of pigmented fungi of the family Dematiaceae. Several fungal genera have been reported to affect humans and other animals including Alternaria, Bipolaris, Cladophialophora (Xylohypha, Cladosporium), Curvularia, Exophiala, Fonsecaea, Moniliella, Phialophora, Ramichloridium, and Scolecobasidium

Although rare in humans, these infections are being reported at an increasing rate. Curvularia is a dematiaceous fungus that is ubiquitous among soil and vegetation in temperate areas and has only recently been revealed to cause human disease. Treatment guidelines have yet to be delineated due so few reported cases. We discuss a 73-year-old man with chronic obstructive pulmonary disease, recent pneumonia caused by Actinomyces, and a localized plaque on his right lateral forearm extending to his medial arm caused by Curvularia species with complete resolution from itraconazole therapy.

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